Mycobacteria

Mycobacterium leprae

Mycobacterium avium complex

Mycobacterium tuberculosis

Acid-fast bacilli, Non-motile, 40% mycolic acid, aerobe, Cat ⨁ Virulence Mycolic acid ⇒ Mycosides Cord factor→ TNF-α ⇒ Cachectia Sulfatid → Inhibit phagolysosome Wax D → Immunogenic Clinic Primary → Lower lobe Asymptomatic → Ghon complex Overt disease in ↓ immune Secondary Pulmonary → Upper lobe cavity Cervical lymph...